Miles & Methods
ResearchAboutRun Tools

Miles & Methods

Think · Explore · Keep Running

ResearchAboutRun ToolsSupport ↗OpenAlex ↗

Note: AI-generated summaries are for educational purposes only and are not medical advice. Always consult a qualified professional before making changes to your training or health routine. Source studies remain the property of their respective publishers.

© 2026 Miles & Methods

Data from OpenAlex

ResearchAboutRun Tools
running meets research

Running science
worth exploring.

Research on training, recovery, longevity, and the running mind — curated by a runner, distilled with AI.

400papers
4categories
∞evergreen
Explore the research
run tools03 / 03
01Race ComparisonPredict from past races02Pace ZonesZones from your pace03Race PredictorFinish time by distance
research feed

The science, distilled.

35 papers
longevity

Does Endurance Exercise Improve Seizure Control? A Study of Persons with Epilepsy Participating in the Dream Run, Tata Mumbai Marathon

International Journal of Epilepsy·2026

Researchers explored whether structured endurance training and participation in a organized running event posed risks or offered benefits for people living with epilepsy — a group historically advised to limit physical activity. Across 56 participants followed over roughly three months, they observed no exercise-triggered seizure worsening and a notable proportion reporting reduced seizure frequency. This is a preliminary, unreviewed observational study, so its findings warrant cautious interpretation.

for runners

For runners curious about how epilepsy and endurance activity intersect, this study suggests the relationship may be less adversarial than longstanding caution implied. What's perhaps most striking is how factors like sleep and medication consistency — not running effort itself — appeared connected to the few negative outcomes observed.

Read paper
AI · not medical advice
longevity

Functional signatures of the gut microbiome in middle-aged regular runners: insights from a metagenomic study

Frontiers in Physiology·2026

Researchers compared the gut microbial ecosystems of middle-aged regular runners against sedentary adults, asking whether years of endurance running leave a detectable signature in the microbiome's composition and functional potential. Despite similar diets and body compositions between groups, distinct microbial patterns emerged in runners — particularly around carbohydrate processing and resistance-related gene profiles. This is a preprint cross-sectional study, so the associations observed cannot establish what caused what.

for runners

For runners curious about the gut-exercise connection, this study underscores that the relationship may be more nuanced than simple diversity differences — functional microbial capacity could matter as much as which species are present. Because this is a cross-sectional preprint without metabolomic validation, these patterns are better understood as intriguing correlations than established effects of running on gut biology.

Read paper
AI · not medical advice
longevity

Impact of Running on the Risk and Progression of Knee Osteoarthritis: A Review of Current Evidence

Cureus·2026

This review examined whether recreational running is harmful or helpful for knee joint health, drawing on evidence published between 2020 and 2024. The researchers observed that the relationship between running and knee osteoarthritis risk appears to follow a curved pattern — with moderate recreational running associated with lower risk than either inactivity or very high-volume elite training. Notably, even in older adults with existing joint changes, running did not appear to accelerate structural deterioration.

for runners

For runners who carry quiet anxiety about what the miles might be doing to their knees over time, this review suggests that concern may be worth reexamining — particularly the assumption that less movement is inherently more protective. The framing of a U-shaped risk curve is an interesting lens: it hints that the knees of a consistent recreational runner may occupy a different risk space than either the couch or the elite start line.

Read paper
AI · not medical advice
longevity

Does Endurance Exercise Improve Seizure Control? A Study of Persons with Epilepsy Participating in the Dream Run, Tata Mumbai Marathon

International Journal of Epilepsy·2026

Researchers explored whether structured endurance training and participation in a organized running event posed risks or offered benefits for people living with epilepsy — a group historically advised to limit physical activity. Across 56 participants followed over roughly three months, they observed no exercise-triggered seizure worsening and a notable proportion reporting reduced seizure frequency. This is a preliminary, unreviewed observational study, so its findings warrant cautious interpretation.

for runners

For runners curious about how epilepsy and endurance activity intersect, this study suggests the relationship may be less adversarial than longstanding caution implied. What's perhaps most striking is how factors like sleep and medication consistency — not running effort itself — appeared connected to the few negative outcomes observed.

Read paper
AI · not medical advice
longevity

Impact of Running on the Risk and Progression of Knee Osteoarthritis: A Review of Current Evidence

Cureus·2026

This review examined whether recreational running is harmful or helpful for knee joint health, drawing on evidence published between 2020 and 2024. The researchers observed that the relationship between running and knee osteoarthritis risk appears to follow a curved pattern — with moderate recreational running associated with lower risk than either inactivity or very high-volume elite training. Notably, even in older adults with existing joint changes, running did not appear to accelerate structural deterioration.

for runners

For runners who carry quiet anxiety about what the miles might be doing to their knees over time, this review suggests that concern may be worth reexamining — particularly the assumption that less movement is inherently more protective. The framing of a U-shaped risk curve is an interesting lens: it hints that the knees of a consistent recreational runner may occupy a different risk space than either the couch or the elite start line.

Read paper
AI · not medical advice
longevity

Functional signatures of the gut microbiome in middle-aged regular runners: insights from a metagenomic study

Frontiers in Physiology·2026

Researchers compared the gut microbial ecosystems of middle-aged regular runners against sedentary adults, asking whether years of endurance running leave a detectable signature in the microbiome's composition and functional potential. Despite similar diets and body compositions between groups, distinct microbial patterns emerged in runners — particularly around carbohydrate processing and resistance-related gene profiles. This is a preprint cross-sectional study, so the associations observed cannot establish what caused what.

for runners

For runners curious about the gut-exercise connection, this study underscores that the relationship may be more nuanced than simple diversity differences — functional microbial capacity could matter as much as which species are present. Because this is a cross-sectional preprint without metabolomic validation, these patterns are better understood as intriguing correlations than established effects of running on gut biology.

Read paper
AI · not medical advice
3 of 35 papers